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CUNO Filter Systems for Bioprocessing/Biologicals

When the question is quality, the answer is CUNO. Genetically-engineered biopharmaceuticals, plasma-derived biologicals, cell culture media and sera, monoclonal antibodies, vaccines and biologically-based diagnostics...

..are some of the world's most valuable products, products that demand the ultimate in purity and quality.

That's why, biopharmaceutical companies and biological manufacturers everywhere turn to CUNO for cost-effective solutions to a wide range of processing challenges - from the clarification of cell culture-derived proteins to the purification of plasma-derived biologicals.

They've discovered that CUNO filter systems consistently provide the requisite purity for the most demanding applications.

CUNO filtration products offer safety, efficacy and superiority. With over 200 patents worldwide, CUNO offers the most advanced and innovative products available for biological separations.

Discover CUNO's innovative solutions for the purification of bioprocess-derived proteins and biologicals.

Bioprocessing

  • Downstream protein purification
  • Chromatography column protection
  • DNA and endotoxin removal
  • Purification of diagnostic serums, reagents, and buffers
  • Cell Culture and Fermentation
  • Plasma Fractionation
  • Sterile Filtration of Biologicals
  • Utilities, Plant Services and Bulk Chemical Filtration

Fermentation

  • Sterile air filtration
  • Bioreactor feed stream clarification and sterilization

Biologicals

  • Clarification of plasma-derived biologicals
  • Clarification of toxoid broths for vaccine manufacturing
  • Allergenic extract filtration

Product Description
BioLIFE™ New cartridge & capsule filters provide clarification of biological fluids and extend the throughput of downstream membranes.
BioASSURE New PES membrane filter combines advanced membrane technology with design innovation.
Betafine® XL ...the Betafine XL filter represents a major advance in pleated filter technology.
Zeta Plus® Generation 2 ...reduces space requirements and zero edge leakage

We also offer a complete line of technical data sheets in PDF format.

  Doc. Code Title Description
Download Product Literature LITZRBIOLIFE1 BioLIFE™ New cartridge & capsule filters provide clarification of biological fluids and extend the throughput of downstream membranes.
Download Product Literature LITCBIOA1 BioASSURE New PES membrane filter combines advanced membrane technology with design innovation
Download Product Literature LITCPN1 PolyNet Increased consumer emphasis on product quality, as well as increased government regulation, are driving today's food & beverage industry to ever-finer levels of filtration. POLYNET filter cartridges meet this challenge throughout its entire service life.
Download Product Literature LITCPN1pb PolyNet PB POLYNET PB filters utilize advanced design and construction to achieve a level of filtration consistency unattainable by competitive filters.
Download Product Literature LITCPN2ADM PolyNet PB Capsule Filters POLYNET PB CAPSULE FILTERS are absolute rated and designed for critical, small volume filter applications in the pharmaceutical, fine chemical and microelectronics markets.
Download Product Literature LITCZC1 ZetaCarbon ZetaCarbon medium incorporates the latest technology to decolorize and remove contaminants from your process streams. ZetaCarbon cartridges and sheets eliminate the concerns of using powdered carbon. In today's manufacturing processes, efficiency, yield, quality and consistency are critical as well as operating in a safe environment for operators. Bulk carbon can also be a limiting step in many operations preventing enhanced yields and increased production batches. ZetaCarbon medium addresses all of these concerns.
Download Product Literature LITZPMAX1 Zeta Plus Maximizer Series CUNO Zeta Plus depth filter cartridges have long been recognized as the premier depth filter in the biotechnology and pharmaceutical industries. Innovative media formulations and cartridge designs, a growing list of patents, and worldwide manufacture point to CUNO's commitment in leading-edge filtration devices. Now added to this well-established family of Zeta Plus filters is the ground-breaking Zeta Plus Maximizer Series.
Download Product Literature LITPXLPB1 PolyPro XL PolyPro XL filter cartridges serve a broad range of prefiltration and clarification applications in pharmaceutical, biological, and bioprocess manufacturing where economy and reliability are critical.
Download Product Literature LITMRFP10601 Microfluor FP Microfluor FP 0.20 micron Pharmaceutical Grade Cartridges are durable, biologically safe and effective filters designed for critical filtration application.
Download Product Literature LITZPS01 Zeta Plus S Series ZETA PLUS S Series Filter Media are patented depth filters composed of inorganic filter aids and cellulose. They are completely free of asbestos and glass microfibers and are ideally suited for pharmaceutical, and cosmetic industry applications.
Download Product Literature LITZPDE1 Zeta Plus Delipid Series ZETA PLUS DELIPID Series is a family of patented depth filter media which incorporates lipid-specific adsorbents for selective removal of lipids, surfactants and biological hydrophobes from human blood plasma, serum-based products, recombinant proteins and other biological fluids.
Download Product Literature LITZRSP3 Zetapor 020SP ZETAPOR 020SP positevly-charged nylon 66 membrane filters are the ideal choice for sterilte filtration and bacterial endotoxin removal from pharmaceutical process fluids.
Download Product Literature LITZPH1P2 12ZP/8ZP Plug-In Models Operating instructions for model 12ZP & 8ZP
Download Product Literature LITHSZPA ZPA Housing Cuno's ZPA HOUSINGS are designed for applications in wine, beer, pharmaceutical, and high-purity water filtration.
Download Product Literature LITZRH104 ZMS/ZVS Housings Manufactured to the strictest of quality standards and from the highest quality materials, the ZVS and ZMS FILTER HOUSINGS meet the exacting requirements of the pharmaceutical, biotechnology, food & beverage and microelectronics industries.
Download Product Literature LITZRH106 ZWB/ZWC Housings Cuno's family of microfiltration products offer a variety of filter media and retention ratings designed to meet the needs of the pharmaceutical, food and beverage, fine chemicals, and microelectronics industries.
Download Product Literature LITCCC2 CUNOCheck 2 Cuno has developed the world's most advanced integrity test instrument, CUNOCHECK 2.
Download Product Literature LITCATBP Bioprocessing Catalog CUNO Filter Systems for Bioprocess and Biological Separations
Download Product Literature LITAPMG2K Zeta Plus Pharmaceutical Selection Guide 2000 Zeta Plus Media Grade Selection Guide for Pharmaceutical, Biological, and Bioprocessing Applications
Download Product Literature LITCLAPB1 LifeASSURE PB Filters Prefilter Cartidges for Pharmaceutical & Biological Service
Download Product Literature LIT50CAPADM 50mm Disposable Filter Capsules CUNO 50 mm capsule filters are ideal for laboratory scale filtration or for evaluating CUNO filter media prior to pilot-scale work.
Download Product Literature CUNO0001 Purification of Microbial Biocatalysts This paper describes the purification of an enzyme from a recombinant strain of Escherichia coli using lenticular filters, and focus ses on the development of ammonium sulphate protein precipitation stages.
Download Product Literature LITCMR2 MicrofluorŽ II: Sterilizing Grade PTFE Filters Microfluor II filters are optimized for applications requiring sterilization of air, gas, or aggressive solvents and chemicals. The hydrophobic PTFE filter membrane prevents wetting with aqueous liquids or moisture that can block free air flow.
Download Product Literature LITZRSTR1 SterASSURE(tm): New FlexN(tm) Multi-Zone Membrane Design SterASSURE filters incorporate an advanced CUNO FlexN membrane technology*. It allows unmatched flexibility in creating a multi-zone membrane that offers maximum contaminant holding capacity while maintaining high retention efficiency.
Download Product Literature LITTDBIOINTART Cell Separation from Mammalian Suspension Cultures Recent years have seen an enormous increase in the production of monoclonal antibodies and recombinant proteins as potential therapeutics using mammalian cell cultures. Production of these complex molecules...
Download Product Literature LITZPZA1 ZETA PLUS ZA Zeta Plus ZA Series - Dept Filter Cartridges Zeta Plus ZA filter medium is composed of pre-extracted inorganic filter aid, cellulose, and a proprietary resin system that imparts a strong positive charge...
Download Product Literature LITZPLA2 ZETA PLUS Low Aluminum CA, SA, & LA Series Filter Media Zeta Plus CA & SA & LA Series Filter Media is manufactured to procedures described in CUNO's Drug Master Files on record with the FDA. They are non-toxic in accordance with the USP Class VI, "Biological Safety Test for Plastics," and meet the strict requirements specified in the Drug Master File, including product control and traceability.
Download Product Literature LITCZPMAX1 Zeta Plus Maximizer™ Series - Depth filter Cartridges and Capsules Zeta Plus filters, a family of advanced cellulose-based depth filtration media, are designed to retain contaminants by both mechanical straining and electrokinetic adsorption. For three decades, CUNO has manufactured Zeta Plus multi-cell cartridge filtration systems which combine high efficiency separations with unmatched filter life in a totally enclosed environment. Zeta Plus systems are used worldwide in bioprocessing and pharmaceutical applications, providing reliable and cost effective filtration.
Download Product Literature LITZPVR Zeta Plus VR Series - Depth Filter Cartridges and Capsules The removal and/or inactivation of contaminating viruses from biotherapeutics is a requisite for ensuring final product safety. Zeta Plus VR cartridge depth filters remove significant levels of viruses from biological fluids. They provide validatable viral titer reduction, high flow rates, scalability, economy, disposability and ease-of-use in the biological manufacturing environment. The VR Series includes specific filter media recommendations for virus removal from blood plasma proteins and bioprocess-derived cell culture fluids.
Download Product Literature LITZPC01 Zeta Plus C Series ZETA PLUS C SERIES filter media are patented depth filters composed of inorganic filter aids and cellulose. They are completely free of asbestos and glass microfibers and are ideally suited for pharmaceutical, food and beverage, and cosmetic industry applications.
Download Product Literature LITZPLP1 Zeta Plus LP Series Zeta Plus LP Series Filters are a depth filter composed of inorganic filter aid and cellulose, extremely low in extractables, and designed specifically for the pharmaceutical industry. The LP Filter Media is constructed with highly purified cellulose to minimize beta-glucan extractables and false positive LAL test results. The positive charge exhibited by Zeta Plus LP Filter Media results in increased particle removal efficiency.
Download Product Literature LITZPMEXTSP1 LITZPMEXTSP1 Zeta Plus Maximizer (TM) EXT with SP Media The new Zeta Plus Maximizer EXT filter with SP media extends depth filter capacity and protection of downstream membranes, thereby extending filter life. Zeta Plus Maximizer EXT filters with SP media are optimized for clarification of mammalian cell harvest fluids and for optimal protection of downstream sterilizing grade membrane filters.
Download Product Literature LITZPMEXT Zeta Plus Maximizer™ EXT with ZA Media The new Zeta Plus Maximizer EXT filter with ZA media extends depth filter capacity and protection of downstream membranes, thereby extending filter life. Zeta Plus Maximizer EXT filters with ZA media are optimized for clarification of mammalian cell harvest fluids and for optimal protection of downstream sterilizing grade membrane filters.
Download Product Literature LITCHF1 CUNO High Flow Filtration System The CUNO High Flow Filtration System is an advanced design that uses 3M Innovation and CUNO's extensive filtration experience to deliver a high flow filter in a compact housing design. When compared to conventional cartridge systems, this system provides high flow capability -- flow rates up to 500 gpm in a single cartridge.

 

 

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